Overview of the Main Molecular Mechanisms of Biological Aging

doi:10.19586/j.2095-2341.2022.0170

Current Biotechnology ›› 2023, Vol. 13 ›› Issue (2): 228-233.DOI: 10.19586/j.2095-2341.2022.0170

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Overview of the Main Molecular Mechanisms of Biological Aging

Wei ZHANG(), Hongfang WANG, Baohua XU()

College of Animal Science and Technology，Shandong Agricultural University，Shandong Taian 271018，China

Received:2022-10-21 Accepted:2023-01-12 Online:2023-03-25 Published:2023-04-07
Contact: Baohua XU

Abstract

Abstract:

Aging is a normal natural law including physical aging and pathological aging. Like other biological processes， it is regulated by some signaling pathways and molecular mechanisms. Through the research on the mechanism of regulating biological aging， it is found that the signaling pathways interact with each other. This paper reviewed three classical signal pathways related to autophagy and delaying aging， including insulin pathway， rapamycin pathway and Sirtuins family， and summarized the main causes and ways of oxidative stress， cell aging and immune aging affecting aging， hoping to discover new interaction pathways and explore more novel molecular mechanisms and methods to prevent， delay or reduce a variety of diseases related to aging.

Key words: aging, signaling pathway, molecular mechanism

CLC Number:

Q419

Wei ZHANG, Hongfang WANG, Baohua XU. Overview of the Main Molecular Mechanisms of Biological Aging[J]. Current Biotechnology, 2023, 13(2): 228-233.

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URL: https://swjsjz.magtechjournal.com/EN/10.19586/j.2095-2341.2022.0170

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Overview of the Main Molecular Mechanisms of Biological Aging

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