Abstract: The Escherichia coli, Bacillus subtilis and Aureus staphylococcus were choosed as strains to measure the impact on the growth inhibition of the synthesized ten 1,4-benzoquinone derivatives by dilution and measurement the size of inhibition zone. The experimental data showed that the higher concentrations of quinones, the higher of inhibitory degree was. Under the same condition of the DMSO solution of these quinones, the bactericidal effect on Escherichia coli and Aureus staphylococcus are better than Bacillus subtilis. The Escherichia coli has slightly higher sensitivity to these quinones than Aureus staphylococcus.

Key words: 1,4-benzoquinone derivatives, bacteriostatic experiments, inhibition zone, Escherichia coli, Bacillus subtilis, Aureus staphylococcus