Bibliometric Analysis of Nucleotide-based Detection Methods for Genetically Modified Plants and Derived Products

doi:10.19586/j.2095-2341.2024.0160

Current Biotechnology ›› 2025, Vol. 15 ›› Issue (3): 476-485.DOI: 10.19586/j.2095-2341.2024.0160

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Bibliometric Analysis of Nucleotide-based Detection Methods for Genetically Modified Plants and Derived Products

Zhi WANG¹(), Guang HU¹, Wei FU², Xuanzi PENG¹, Yongjiang ZHANG¹(), Junfeng ZHAI¹()

^1.Chinese Academy of Quality and Inspection & Testing，Beijing 100176，China
^2.Development Center for Science and Technology，Ministry of Agriculture and Rural Affairs，Beijing 100176，China

Received:2024-10-15 Accepted:2024-12-03 Online:2025-05-25 Published:2025-07-01
Contact: Yongjiang ZHANG,Junfeng ZHAI

基于文献计量的转基因植物及其产品核酸检测技术发展态势分析

王智¹(), 胡广¹, 付伟², 彭萱子¹, 张永江¹(), 翟俊峰¹()

^1.中国质量检验检测科学研究院，北京 100176
^2.农业农村部科技发展中心，北京 100176

通讯作者: 张永江,翟俊峰
作者简介:王智E-mail： wangzhi6666@126.com
基金资助:
农业生物育种国家科技重大专项(2022ZD04020);海南省重点研发项目(ZDYF2024XDNY160)

Abstract

Abstract:

With the expanding variety and quantity of genetically modified （GM） plants and their derived products， requirements for nucleic acid detection precision have become increasingly stringent. This study utilized the Web of Science Core Collection database， employing bibliometric methods to comprehensively analyze research trends， primary directions， global research capacity distribution， and China’s scientific standing in GM nucleic acid detection technology. The analysis results showed that as of early 2023， the total number of SCI related to nucleic acid testing technology has reached 2 550， and China ranks first in the global publication volume in this field. More than 90 countries/regions and approximately 2 400 institutions worldwide have participated in the research of GM nucleic acid testing technology. Among the top 20 institutions in terms of publication volume， 7 of them are from China. Among the 30 high-quality journal articles related to GM nucleic acid detection technology， 14 are from China， indicating that relevant research in China has shown a trend of high-quality development. At the same time， this article summarized the current status of different GM nucleic acid testing technologies from multiple dimensions such as paper publication trends， publication volume， and publishing institutions， and analyzed the differences in research trends of the above technologies， aiming to ensure the efficient utilization of scientific research resources and provide data support for regulatory agencies’ strategic decision-making and research directions.

Key words: bibliometric, Web of Science, research trends, transgene, detection technology

摘要：

随着转基因植物及其产品的种类和数量日益增多，对核酸检测技术的精确度要求也越来越高。基于Web of Science的Science Citation Index（SCI）核心数据库，从文献计量学的角度，对转基因核酸检测技术的主要研究方向、研究趋势、科研实力分布以及中国在该领域的科研水平进行了全面的统计分析。分析结果显示，截至2023年初，与核酸检测技术相关的SCI论文总数已达到2 550篇，我国在该领域的全球发文量位列首位。全球超过90个国家/地区和约2 400家机构参与了转基因核酸检测技术的研究工作。发文量排名前20位的机构中，其中有7家机构来自于中国。涉及转基因核酸检测技术的30篇高质量期刊论文中，有14篇来自于中国，这一结果表明我国相关研究已呈现出高质量发展态势。同时，针对目前主要的8种核酸检测技术，从论文发表趋势、发文量及发文机构等多个维度对不同转基因核酸检测技术现状进行总结并分析上述技术的研究态势差异，旨在确保科研资源的高效利用，并为监管机构的战略决策和研究方向提供数据支持。

关键词: 文献计量, Web of Science, 研究态势, 转基因, 检测技术

CLC Number:

Q789

Zhi WANG, Guang HU, Wei FU, Xuanzi PENG, Yongjiang ZHANG, Junfeng ZHAI. Bibliometric Analysis of Nucleotide-based Detection Methods for Genetically Modified Plants and Derived Products[J]. Current Biotechnology, 2025, 15(3): 476-485.

王智, 胡广, 付伟, 彭萱子, 张永江, 翟俊峰. 基于文献计量的转基因植物及其产品核酸检测技术发展态势分析[J]. 生物技术进展, 2025, 15(3): 476-485.

Figures/Tables 20

Fig. 1 Research paper publication trend on transgenic nucleic acid detection methods from 1990 to 2022

Fig. 2 Distribution of Top 15 countries in transgenic nucleic acid detection research publications

Table 1 Top 20 research institutions in transgenic nucleic acid detection

机构名称	论文数/篇	所占比例/%
农业农村部及直属机构（不含中国农业科学院）	116	4.55
中国农业科学院	100	3.92
日本国家农业与食品研究机构	87	3.41
日本国立医药品食品卫生研究所	73	2.86
上海交通大学	70	2.75
欧盟委员会联合研究中心	63	2.47
中国农业大学	60	2.35
中国科学院	49	1.92
法国UDICE大学	48	1.88
法国国家农业食品与环境研究院	45	1.77
印度农业研究理事会	41	1.61
韩国庆熙大学	38	1.49
西班牙高等科研理事会	38	1.49
浙江大学	35	1.37
美国加州大学系统	34	1.33
斯洛文尼亚国家生物研究所	34	1.33
日本FASMAC公司	33	1.29
浙江省农业科学院	29	1.14
巴黎萨克雷大学	29	1.14
美国农业部	29	1.14

Table 2 Top 10 distribution of publications on transgenic nucleic acid detection technology among major countries

国家	qPCR	dPCR	mPCR	LAMP	RPA	Microarray	CRISPR/Cas检测	快速检测	合计
合计	707	84	187	65	23	6	29	362	1 463
中国	227	35	60	40	23	2	24	159	570
美国	77	13	13	4	0	0	1	79	187
日本	66	6	18	5	0	1	1	40	137
德国	76	5	15	0	0	0	2	29	127
印度	42	0	23	11	0	0	0	20	96
意大利	62	4	13	1	0	0	0	14	94
韩国	27	0	33	1	0	3	1	21	86
比利时	68	8	0	1	0	0	0	0	77
瑞士	29	4	12	1	0	0	0	0	46
斯洛文尼亚	33	9	0	1	0	0	0	0	43

Fig. 3 The distribution of publication years for qPCR detection methods from 2000 to 2022

Fig. 4 The distribution of institutions that published papers on qPCR detection methods

Fig. 5 The distribution of publication years for dPCR detection methods from 2000 to 2022

Fig. 6 The distribution of institutions that published papers on dPCR detection methods

Fig. 7 The distribution of publication years for mPCR detection methods from 2000 to 2022

Fig. 8 The distribution of institutions that published papers on mPCR detection methods

Fig. 9 The distribution of publication years for LAMP detection methods from 2000 to 2022

Fig. 10 The distribution of institutions that published papers on LAMP detection methods

Fig. 11 The distribution of publication years for RPA detection methods from 2000 to 2022

Fig. 12 The distribution of institutions that published papers on RPA detection methods

Fig. 13 The distribution of publication years for microarray detection methods from 2000 to 2022

Fig. 14 The distribution of institutions that published papers on microarray detection methods

Fig. 15 The distribution of publication years for CRISPR/Cas detection methods from 2000 to 2022

Fig. 16 The distribution of institutions that published papers on CRISPR/Cas detection methods

Fig. 17 The distribution of publication years for rapid detection methods from 2000 to 2022

Fig. 18 The distribution of institutions that published papers on rapid detection methods

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Bibliometric Analysis of Nucleotide-based Detection Methods for Genetically Modified Plants and Derived Products

基于文献计量的转基因植物及其产品核酸检测技术发展态势分析

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