Progress and Prospect of CRISPR/Cas System Research and Development

doi:10.19586/j.2095-2341.2017.0091

Curr. Biotech. ›› 2017, Vol. 7 ›› Issue (6): 594-600.DOI: 10.19586/j.2095-2341.2017.0091

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Progress and Prospect of CRISPR/Cas System Research and Development

WANG Youhua, ZOU Wannong, KANG Yuli, TANG Qiaoling, SUN Guoqing

The Ministry of Agriculture Key Laboratory for Agricultural Genomics（Beijing）, Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing 100081, China

Received:2017-07-17 Online:2017-11-25 Published:2017-08-28

CRISPR/Cas系统研发进展及展望

王友华,邹婉侬,康宇立,唐巧玲,孙国庆*

中国农业科学院生物技术研究所, 农业部农业基因组学重点实验室（北京）, 北京 100081

通讯作者: 孙国庆，研究员，主要从事科技管理、知识产权研究。E-mail:sunguoqing01@caas.cn
作者简介:王友华，助理研究员，主要从事科技管理、知识产权研究。E-mail:wangyouhua@caas.cn。
基金资助:
中央级公益性科研院所基本科研业务费（1610392016011）资助。

Abstract

Abstract: Clustered regularly interspaced short palindromic repeats (CRISPR) has been found for 20 years until now. But since the successful application of the first CRISPR/Cas gene editing, CRISPR achieves rapid development in the pharmaceutical, agriculture and environmental protection in a short time. This paper summarized the progress on classification and application of CRISPR/Cas system. We also reviewed the status, hotspot, trend of research and development in current field, and put forward the expectation for future of CRISPR/Cas technology application.

Key words: CRISPR/Cas, system classification, application field

摘要： 成簇间隔的短回文重复序列(clustered regularly interspaced short palindromic repeat sequences，CRISPR)发现至今已有20年，但从第一个CRISPR/Cas基因编辑的成功应用至今，其在医药、农业、环保等领域短时间内即有了迅猛发展。归纳总结了CRISPR/Cas系统的分类和应用进展，阐述了该技术的研发现状、研究热点与发展态势，并对CRISPR/Cas技术的应用前景提出展望。

关键词: CRISPR/Cas, 系统分类, 应用领域

WANG Youhua, ZOU Wannong, KANG Yuli, TANG Qiaoling, SUN Guoqing*. Progress and Prospect of CRISPR/Cas System Research and Development[J]. Curr. Biotech., 2017, 7(6): 594-600.

王友华,邹婉侬,康宇立,唐巧玲,孙国庆. CRISPR/Cas系统研发进展及展望[J]. 生物技术进展, 2017, 7(6): 594-600.

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Progress and Prospect of CRISPR/Cas System Research and Development

CRISPR/Cas系统研发进展及展望

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