Abstract: Sodium gluconate was produced through fermentation by Aspergillus niger. Fermentation parameter was detected and monitored to study the variation of the parameters of fermentation and physiological activities of Aspergillus niger. The fermentation process was optimized through the orthogonal test. The optimum conditions were as follows: 16.5 h seed; 15% inoculation quantity, pH 5.8. Antibacterial effect of sodium gluconate was verified, and the results showed that the amount of sodium gluconate as feed additive could be 0.5% to 0.7%, which provide a theoretical basis for the application of sodium gluconate in the feed industry.

Key words: sodium gluconate, antibacterial effect, feed additive

摘要： 利用黑曲霉发酵法生产葡萄糖酸钠，通过参数检测研究各参数及黑曲霉生理活性的变化规律。通过正交试验优化发酵，最终确定发酵参数为：16.5 h种龄、15%转种量和pH 5.8。验证葡萄糖酸钠抑菌效果，最终确定饲料中可添加量为0.5%~0.7%，为葡萄糖酸钠在饲料行业中的应用提供理论依据。

关键词: 葡萄糖酸钠, 抑菌效果, 饲料添加剂