Curr. Biotech. ›› 2017, Vol. 7 ›› Issue (2): 111-115.DOI: 10.3969/j.issn.2095-2341.2017.02.05

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Progress on  Biosynthesis Pathway and Function of Key Enzyme in Raspberry Ketone

ZHANG Fenqiang, LIU Huan, HUANG Lina, JIANG Mengyan, ZHOU Yijie, ZOU Yuchen, YANG Mingfeng, MA Lanqing,#br#   

  1. 1.Key Laboratory of Urban Agriculture (North China), Ministry of Agriculture, Plant Science and Technology College, Beijing University of Agriculture,  Beijing 102206, China
    2.Key Laboratory of Urban Agriculture (North China), Ministry of Agriculture, College of Biological Science and Engineering, Beijing University of Agriculture, Beijing 102206, China;
    3.Beijing Collaborative Innovation Center for Eco-environmental Improvement with Forestry and  Fruit Trees, Beijing University of Agriculture, Beijing 102206, China
  • Received:2016-11-16 Online:2017-03-25 Published:2016-12-14

树莓酮生物合成途径及关键酶功能研究进展

张奋强1,刘欢1,黄丽娜2,姜梦嫣2,周义杰1,邹宇晨2,杨明峰2*,马兰青2,3*   

  1. 1.北京农学院植物科学技术学院, 农业部华北都市农业重点实验室, 北京 102206;
    2.北京农学院生物科学与工程学院, 农业部华北都市农业重点实验室, 北京 102206;
    3.北京农学院, 北京林果业生态环境功能提升协同创新中心, 北京 102206
  • 通讯作者: 杨明峰，副教授，研究方向为植物分子生物学和植物代谢调控研究。E-mail: mingfengyang@bua.edu.cn；马兰青，教授，研究方向为植物次生代谢分子调控。E-mail：lqma713@163.com
  • 作者简介:张奋强，硕士研究生，研究方向为果树品质优质生态安全。E-mail: huanliu0824@163.com。
  • 基金资助:
    国家自然科学基金项目(21606020)；北京市自然科学基金项目(2164059);北京市科技创新服务能力建设-协同创新中心项目（PXM2017_014207_000043）资助。

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Abstract: Raspberry ketone is a kind of aroma compound, its chemical name is 4-(4-hydroxyphenyl)-2-butanone, which is existing in many kinds of plants. Raspberry ketone is not only applied in food industries and comestic industries as its unique flavor, but also has good effect on loseing weight. The cost that abstract raspberry ketone from plants is exceedingly high and the yield is very low, which leads high price of  raspberry ketone. So through metabolic engineering to synthesize raspberry ketone has become research hotspots recently. In recent ten years, there are many research  on  biosynthesis pathway of raspberry ketone at home and abroad. The paper summarized the achivements on  biosynthesis pathway of raspberry ketone and proposed some opinions, which was expected to provide reference for further study on raspberry ketone biosynthesis.

 

Key words: raspberry ketone, biosynthesis pathway, research progress

摘要： 树莓酮（raspberry ketone），又称覆盆子酮，其化学名称为4-对羟基苯基-2-丁酮[4-(4-hydroxyphenyl)-2-butanone]，是存在于多种植物中的香气化合物。树莓酮不仅因其独特的香味被食品行业和化妆品行业应用，而且树莓酮有很好的减肥作用。由于从植物中提取树莓酮的成本非常高，而且产量少，导致市售的树莓酮价格含量极高。因此通过代谢工程的方法来合成树莓酮成为近年来研究的热点。近十几年来，国内外对于树莓酮的生物合成途径做了大量的研究。总结了近十几年来国内外对于树莓酮生物合成途径的成果，并在此基础上提出了对于树莓酮生物合成的一些见解,以期对树莓酮生物合成途径的研究有所启发。

关键词: 树莓酮, 生物合成, 研究进展

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