Current Biotechnology ›› 2023, Vol. 13 ›› Issue (2): 210-219.DOI: 10.19586/j.2095-2341.2022.0131

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Research Progress on Production and Application of Mannosylerythritol Lipids

Siyuan QIU(), Jingxue XU(), Yuyang DUAN, Jinyu ZHAO, Wenjing ZHAO, Lixin ZHANG, Guoling REN   

  1. College of Bioengineering,Daqing Normal University,Heilongjiang Daqing 163712,China
  • Received:2022-07-12 Accepted:2022-11-17 Online:2023-03-25 Published:2023-04-07
  • Contact: Jingxue XU

Abstract:

As a type of biosurfactant, mannosylerythritol lipids (MELs) have merits with biodegradability, low toxicity and good biocompatibility. Due to its distinct structural, metabolic, and synthetic features, it also performs a wide range of other tasks, including skin restoration, gene transfection, and broad-spectrum antibacterial activity. MELs has a promising future in a number of industries, including medicine, daily chemicals, food, agriculture, and ecological restoration, which is widely recognized as one of the most promising biosurfactants. However, because of the great structural heterogeneity, backward manufacturing style of MELs generated by various species, hazy synthesis and uncertain mechanism of action, it is hard to carry out large-scale commercial production. The paper aimed to clarify the diversity of its structure and function, so as to provide reference for the realization of customized production targeting MELs. By focusing on the aspects of structural characteristics, production purification, application path and so on, the paper was hoped to help reduce the production cost and accelerate the realization of its large-scale application.

Key words: mannosylerythritol lipids, bio-surfactants, microorganism

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