Some Key Scientific Questions in Utilization of Selenium Resources in China

doi:10.19586/j.2095-2341.2021.0104

Current Biotechnology ›› 2021, Vol. 11 ›› Issue (4): 542-549.DOI: 10.19586/j.2095-2341.2021.0104

• Human Health and the Environment • Previous Articles

Some Key Scientific Questions in Utilization of Selenium Resources in China

Huawei ZANG¹^,²(), Zezhou ZHANG³(), Zedong LONG⁴(), Wenyao SHI¹(), Xuebin YIN³, Yongxian LIU⁵, Linxi YUAN¹()

^1.Department of Health and Environmental Sciences，Xi’an Jiaotong?Liverpool University，Jiangsu Suzhou 215123，China
^2.School of Earth and Space Sciences，University of Science and Technology of China，Hefei 230026
^3.Key Lab on Functional Agriculture，Suzhou Institute for Advanced Study，University of Science and Technology of China，Jiangsu Suzhou 215123，China
^4.Institute of Soil and Fertilizer，Hunan Academy of Agricultural Sciences，Changsha 410125，China
^5.Agricultural Resource and Environment Research Institute，Guangxi Academy of Agricultural Sciences，Nanning 530007，China

Received:2021-06-06 Accepted:2021-06-28 Online:2021-07-25 Published:2021-08-02
Contact: Linxi YUAN

中国硒资源利用中若干关键科学问题的探讨

臧华伟¹^,²(), 张泽洲³(), 龙泽东⁴(), 施文尧¹(), 尹雪斌³, 刘永贤⁵, 袁林喜¹()

^1.西交利物浦大学健康与环境科学系，江苏苏州 215123
^2.中国科学技术大学地球与空间科学学院，合肥 230026
^3.中国科学技术大学苏州高等研究院功能农业重点实验室，江苏苏州 215123
^4.湖南省农业科学院土壤肥料研究所，长沙 410125
^5.广西农业科学院农业资源与环境研究所，南宁 530007

通讯作者: 袁林喜
作者简介:臧华伟 E-mail:zanghw01@163.com
张泽洲 E-mail:280602128@qq.com
龙泽东 E-mail:lzd313@mail.ustc.edu.cn
施文尧 E-mail:shiwenyao@yahoo.com第一联系人：（臧华伟、张泽洲、龙泽东、施文尧并列第一作者）
基金资助:
国家自然科学基金项目(31400091);广西科技重大专项(桂科AA17202026-6);湖北恩施科技局国际合作专项(XYJ2018000080)

Abstract

Abstract:

China is a typical selenium （Se） deficient country with a saddle Se?deficiency soil belt across Northeast to Southwest， accounting for 33.34% in the main agricultural areas. However， there are also spot?like Se?rich/high areas， accounting for 8.69% in the main agricultural areas， which are widely explored to produce Se?rich agriculture products， such as Enshi/Hubei， Ankang/Shaanxi， Shitai/Anhui， Bama/Guangxi， and Yichun/Jiangxi. Along with the utilization of Se resources， some scientific questions have been widely raised， such as： does Se intake have health effects？ Is there any evidence from the population in natural Se?rich areas？ How is the toxicity of Cd in Se?rich products？ Why should we pay attention to Se speciation rather than total Se contents？ What is the mechanism of Se hyperaccumulation in Cardamine hupingshanensis？ Based on our researches on natural Se resources in recent ten years， the present review provided some perspectives on the above scientific questions and was expected to spot some lights on the efficient and safe utilization of Se resources in the future in China.

Key words: Se resources, hair Se levels, blood Se levels, co?existence of Se and Cd, Se speciation, Cardamine hupingshanensis

摘要：

中国是典型缺硒大国，一条马鞍形土壤缺硒带呈东北-西南走向分布，占主要农耕区土壤面积的33.34%，但同时也存在点状分布的富硒-高硒地区，占主要农耕区土壤面积的8.69%，成为湖北恩施、陕西安康、安徽石台、广西巴马、江西宜春等地方农业转型升级的新抓手，得到大力开发利用。伴随着硒资源的开发利用，一些科学问题被广泛提出，如：硒摄入有何健康效果？天然富硒区人群是否有实证研究数据？硒-镉共生导致天然富硒农产品富硒的同时是否存在镉含量超标问题？硒资源中的硒形态组成有何重要意义？硒超积累植物-壶瓶碎米荠的超积累硒的机制是什么？这些关键科学问题亟待解答。基于对天然硒资源近10年的研究成果，对以上科学问题进行了一些有益探讨，以期为未来高效安全科学地利用硒资源提供一些研究思路。

关键词: 硒资源, 发硒, 血硒, 硒-镉共存, 硒形态, 壶瓶碎米荠

CLC Number:

Huawei ZANG, Zezhou ZHANG, Zedong LONG, Wenyao SHI, Xuebin YIN, Yongxian LIU, Linxi YUAN. Some Key Scientific Questions in Utilization of Selenium Resources in China[J]. Current Biotechnology, 2021, 11(4): 542-549.

臧华伟, 张泽洲, 龙泽东, 施文尧, 尹雪斌, 刘永贤, 袁林喜. 中国硒资源利用中若干关键科学问题的探讨[J]. 生物技术进展, 2021, 11(4): 542-549.

References 48

1	袁丽君, 袁林喜, 尹雪斌,等. 硒的生理功能、摄入现状与对策研究进展[J]. 生物技术进展, 2016(6): 396-405.
2	吴春蕾, 吴之琳, 吴洁,等. 硒在植物保护与农产品质量安全中的应用进展[J]. 生物技术进展, 2017, 7(5): 462-466.
3	李海蓉, 杨林生, 谭见安,等. 我国地理环境硒缺乏与健康研究进展[J]. 生物技术进展, 2017, 7(5): 381-386.
4	王锐, 余涛, 曾庆良,等. 我国主要农耕区土壤硒含量分布特征、来源及影响因素[J]. 生物技术进展, 2017(5): 359-366.
5	李卫东, 万海英, 朱云芬, 等. 恩施州天然硒资源特征及其开发利用研究进展[J]. 生物技术进展, 2017, 7(5): 545-550.
6	唐德剑, 夏曾润. 陕西安康硒资源开发现状及其产业化对策研究[J]. 生物技术进展, 2017, 7(5): 551-556.
7	何邵麟, 陈武, 莫春虎, 等. 贵州乌蒙山区土壤-农作物体系硒-锌分布特征研究[J]. 生物技术进展, 2017,7(5): 557-562.
8	YUAN L, ZHU Y, LIN Z Q, et al.. A novel selenocystine-accumulating plant in selenium-mine drainage area in Enshi, China[J/OL]. PLoS ONE, 2013, 8(6): e65615[2021-06-29]. .
9	国家卫生健康委员会. 新食品原料终止审查目录-堇叶碎米荠[EB/OL]. , 2021.
10	袁林喜. 嗜硒微生物Wautersiella enshiensis sp. nov. YLX-1 及其应用: ZL 201510547673.3[P]. 中国,2015-12-09.
11	袁林喜. 氧化微杆菌Microbacterium oxydans YLX-2及其应用: ZL 201510547681.8[P]. 中国, 2015-12-09.
12	袁林喜. 苏云金芽孢杆菌Bacillus thuringiensis YLX-4及其应用: ZL 201510547403.2[P]. 中国,2015-12-30.
13	袁林喜. 高山芽孢杆菌Bacillus altitudinis YLX-5及其应用: ZL201510547672.9[P]. 中国,2015-12-30.
14	ZHANG L, SONG H, GUO Y, et al.. Benefit-risk assessment of dietary selenium and its associated metals intake in China (2017-2019): Is current selenium-rich agro-food safe enough?[J/OL] J. Hazard. Mater., 2020, 398: 123224[2021-06-29]. .
15	龙泽东. 硒在天然富硒区恩施与石台土壤-作物-人体系统中的分布特征和健康效应研究[D]. 合肥:中国科学技术大学,博士学位论文, 2020.
16	VINCETI M, CHAWLA R, FILIPPINI T, et al.. Blood pressure levels and hypertension prevalence in a high selenium environment: results from a cross-sectional study[J]. Nutr. Metab. Cardiovasc. Dis., 2019, 29(4): 398-408.
17	LOOMBA R, FILIPPINI T, CHAWLA R, et al.. Exposure to a high selenium environment in Punjab, India: Effects on blood chemistry[J/OL]. Sci. Total Environ., 2020, 716: 135347[2021-06-29]. .
18	程义勇. «中国居民膳食营养素参考摄入量»2013修订版简介[J]. 营养学报, 2014, 36(4): 313-317.
19	XIE C, XIAN J, ZENG M, et al.. Regional difference in the association between the trajectory of selenium intake and hypertension: a 20-year cohort study[J/OL]. Nutrients, 2021, 13(5): 1501[2021-07-10]. .
20	HAO Z, LI Y H, LIU Y, et al.. Hair elements and healthy aging: a cross-sectional study in Hainan Island, China[J]. Environ. Geochem. Health., 2016, 38(3): 723-735.
21	HAO Z, LIU Y, LI Y H, et al.. Association between longevity and element levels in food and drinking water of typical Chinese longevity area[J]. J. Nutr. Health Aging, 2016, 20(9): 1-7.
22	LI Z, ZENG H, CHENG W H. Beneficial and paradoxical roles of selenium at nutritional levels of intake in healthspan and longevity[J]. Free Radic. Biol. Med., 2018, 127: 3-13.
23	袁知洋, 项剑桥, 吴冬妹, 等. 恩施富硒土壤区主要农作物硒镉特征以及和根系土硒镉关系研究[J]. 资源环境与工程, 2017, 31(6): 706-712.
24	DU Y J, LUO K L, NI R X, et al.. Selenium and hazardous elements distribution in plant-soil-water system and human health risk assessment of Lower Cambrian, Southern Shaanxi, China[J]. Environ. Geochem. Health., 2018, 40: 2049-2069.
25	YANG B B, YANG C, SHAO Z Y, et al.. Selenium (Se) does not reduce cadmium (Cd) uptake and translocation in rice (Oryza sativa L.) in naturally occurred Se-rich paddy fields with a high geological background of Cd[J]. Bull Environ. Contam. Toxicol., 2019, 103(1): 127-132.
26	ZHANG Z, YUAN L, QI S, et al.. The threshold effect between the soil bioavailable molar Se: Cd ratio and the accumulation of Cd in corn (Zea mays L.) from natural Se-Cd rich soils[J]. Sci. Total Environ., 2019, 688: 1228-1235.
27	HOFFMANN P R, BERRY M J. The influence of selenium on immune responses[J]. Mol. Nutr. Food Res., 2010, 52(11):1273-1280.
28	GROMADZIŃSKA J, RESZKA E, BRUZELIUS K, et al.. Selenium and cancer: biomarkers of selenium status and molecular action of selenium supplements[J]. Eur. J. Nutr., 2008, 47(2): 29-50.
29	LIU L L, LI C M, ZHANG Z W, et al.. Protective effects of selenium on cadmium-induced brain damage in chickens[J]. Biol. Trace Elem. Res., 2014, 158(2): 176-185.
30	蔡秋, 张明忠, 刘康书, 等. 硒摄入对肉牛组织中镉、铅、铜、铁、锌含量的影响[J]. 中国畜牧杂志, 2012, 48(09): 47-50.
31	LI L L, WU Q Z, CHEN J J, et al.. Mechanical Insights into thiol-mediated synergetic biotransformation of cadmium and selenium in nematodes[J/OL]. Environ. Sci. Tech., 2021, doi:doi.org/10.1021/acs.est.1c00686[2021-06-28]..
32	朱建明, 梁小兵, 凌宏文, 等. 环境中硒存在形式的研究现状[J]. 矿物岩石地球化学通报, 2003, 22(1): 75-81.
33	KABATA-PENDIAS. A. Geochemistry of selenium[J]. J. Environ. Pathol. Toxicol. Oncol., 1998, 17(3-4): 173-177.
34	TERRY N, ZAYED A M, TARUN A S, et al.. Selenium in higher plants[J]. Annu. Rev. Plant Physiol. Plant Mol. Biol., 2000, 51(1): 401-432.
35	ZHOU X, YANG J, KRONZUCKER H J, et al.. Selenium biofortification and interaction with other elements in plants: a review[J]. Front. Plant Sci., 2020, 11: 586421.
36	SCHIAVON M, NARDI S, VECCHIA F D, et al.. Selenium biofortification in the 21st century: status and challenges for healthy human nutrition[J]. Plant Soil, 2020(3): 1-26.
37	PATTERSON B H, ZECH L A, SWANSON C A, et al.. Kinetic modeling of selenium in humans using stable-isotope tracer[J]. J. Trace Elem. Elctrol. Health Dis., 1993, 7(2): 117-120
38	HATFIELD D L, SCHWEIZER U, TSUJI P, et al.. Selenium: Its Molecular Biology and Role in Human Health (fourth edition)[M]. New York: Springer Science Press, 2016.
39	FAIRWEATHER-TAIT S J, BAO Y, BROADLEY M R, et al.. Selenium in human health and disease[J]. Antioxi. Redox Signal., 2011, 14(7): 1337-1383.
40	王磊, 杜菲, 孙卉, 等. 人体硒代谢与硒营养研究进展[J]. 生物技术进展, 2015, 5(4): 285-290.
41	张泽洲. 典型农作物中硒形态分析及其硒-镉互作研究[D]. 武汉:中国地质大学,博士学位论文, 2019.
42	LU X, HE Z, LIN Z, et al.. Effects of Chinese cooking methods on the content and speciation of selenium in selenium bio-fortified cereals and soybeans[J/OL]. Nutrients, 2018, 10(3): 317[2021-06-29].
43	陶旭. 施硒对壶瓶碎米荠生长,生理特性及硒积累的影响[D]. 安徽芜湖:安徽师范大学,硕士学位论文, 2016.
44	ZAMBRANO M C, YUAN L X, YIN X B, et al.. Element case study: Selenium[M]// Agromining: Farming for Metals-Extracting Unconventional Resources Using Plants (eds. 2nd edition). Springer International Publishing AG, 2021.
45	陆晓奇, 王健, 朱元元, 等. 典型富硒植物中硒形态和生物可给性研究[J]. 土壤, 2018, 50(6): 1229-1234.
46	袁林喜, 张影. 硒超积累植物壶瓶碎米荠的根际微生物特征研究[J]. 生物技术进展, 2017, 7(5): 395-401.
47	TONG X Z, YUAN L X, LUO L, et al.. Characterization of a selenium-tolerant rhizosphere strain from a novel Se-hyperaccumulating plant Cardamine hupingshanensis [J/OL]. Sci. World J., 2014: 108562[2021-06-29].
48	张如, 樊霆, 李淼, 等. 一株耐硒壶瓶碎米荠内生菌分离、鉴定及其体外硒代谢研究[J]. 微生物学通报, 2018, 45(2): 314-321.

Some Key Scientific Questions in Utilization of Selenium Resources in China

中国硒资源利用中若干关键科学问题的探讨

RichHTML

PDF

Knowledge

Abstract

Cite this article

share this article

References 48

Related Articles 0

Recommended Articles

Metrics

Comments