Abstract: A series of physiological and mentality changes would take place in many organs and bodily systems of organism under the conditions of weightlessness or simulated weightlessness. Given the brain “central controller” role and its basic function of executive control was motion, sensation, cognition, emotion and memory. The damage of brain function could affect the accomplishment of space mission and the progress of space career. Thus, the influence of weightlessness or simulated weightlessness to brain plays an important role in the research of aerospace medicine. The research progress on the influence of weightlessness or simulated weightlessness to brain function was reviewed in this paper, and the mechanism was demonstrated through its effect on nervous system and vascular, which was expected to provide reference for related research on reduction influences of weightlessness or simulated weightlessness to brain.

Key words: weightlessness, simulated weightlessness, brain function

摘要： 在失重或模拟失重环境中,机体会经历一系列的生理和心理变化。大脑作为“中央控制器”，其基本功能是控制运动、感觉、认知、情感和记忆等。大脑功能受损将直接影响航天任务的完成，影响航天事业的发展。因此，失重或模拟失重对大脑的影响是航天医学亟待解决的重要问题。综述了失重或模拟失重对大脑功能影响的研究现状，并且从其对神经系统、血管的影响说明其作用机制，以期为解决失重对大脑功能造成的影响相关研究提供参考。

关键词: 失重, 模拟失重, 大脑功能