关键词: 硒, 纳米硒, 抗氧化, 抗癌, 毒性

Abstract: Selenium (Se) is an essential trace element to human, with multiple biological functions of anti-aging, free radical scavenging, cardiovascular protection, anti-cancer, etc. However, the application of Se in healthy food and pharmaceutical products has been limited by the fact that the therapeutic and toxic doses range of traditional Se compounds are too close. Se nanoparticles (SeNPs) is a novel Se species discovered in recent years. This review focused on the development of toxicity and biomedical effects of SeNPs, including anti-oxidant, anti-cancer, anti-bacterial, potential as a dietary supplement, etc. Additionally, we gave some prospects for future researches, which was expected to provide references for the biomedical application of SeNPs and protection of human health.

Key words: selenium, selenium nanoparticles, anti-oxidation, anti-cancer, toxicity