生物技术进展 ›› 2011, Vol. 1 ›› Issue (3): 184-188.DOI: 10.3969/j.issn.2095-2341.2011.03.06
• 卷首语 • 上一篇 下一篇
姜利滨,文莹,陈芝*
收稿日期:
出版日期:
发布日期:
通讯作者:
作者简介:
基金资助:
农业部微生物资源与利用开放重点实验室青年基金项目(201002)资助。
JIANG Li-bin, WEN Ying, CHEN Zhi
Received:
Online:
Published:
摘要： 分选酶(sortase)普遍存在于革兰氏阳性细菌中,是一类膜结合的转肽酶,负责将表面蛋白共价结合到细胞壁的肽聚糖上。由于其独特的作用机制,分选酶在生物技术领域具有广阔的应用前景,可应用于革兰氏阳性菌的表面展示、蛋白质工程等。
关键词: 分选酶, 表面蛋白, 表面展示, 蛋白质连接
Abstract: Sortases are membrane-bound transpeptidases produced by Gram-positive bacteria to anchor cell surface proteins covalently to peptidoglycan in the cell wall. Due to its specific reaction, sortases are exploited for a range of biotechnology application, such as Gram-positive bacterial cell-surface display and protein engineering, etc. This paper reviews research progress on sortase and its application in biotechnology.
Key words: sortase, surface protein, surface display, protein linkage
姜利滨,文莹,陈芝. 分选酶的研究进展及其在生物技术中的应用[J]. 生物技术进展, 2011, 1(3): 184-188.
JIANG Li-bin, WEN Ying, CHEN Zhi*. Research Progress on Sortase and its Application in Biotechnology[J]. journal1, 2011, 1(3): 184-188.
0 / / 推荐
导出引用管理器 EndNote|Ris|BibTeX
链接本文: https://swjsjz.magtechjournal.com/CN/10.3969/j.issn.2095-2341.2011.03.06
https://swjsjz.magtechjournal.com/CN/Y2011/V1/I3/184
